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Bone Cancer: Apoptosis and Drug Resistance in Malignant Bone Tumors

By: , Posted on: September 10, 2014

Bone Cancer, 2nd EditionThe second edition of Bone Cancer: Primary Bone Cancers and Bone Metastases is the only translational reference to cover all aspects of primary bone cancer and bone metastases from basic science to clinical analysis and new therapeutic approaches. Published just last month (August), the book comprehensively investigates key discoveries in the field of bone biology over the last five years that have led to the development of entirely new areas for investigation, such as therapies which combine surgery and biological approaches.

 

 

About the Author

Dominique HeymannDominique Heymann studied cell biology, biochemistry and immunology in INSERM (French NIH) unit 211 at the University of Nantes and received his Ph.D. in 1995. He was appointed Associate Professor in 2001 in the Department of Histology and Embryology. In 2009, he was awarded a personal Chair of Histology and Embryology. Currently he is the Quality Control Manager of the Tissue Bank and Gene and Cellular Therapy Unit at Nantes Hospital. He heads a laboratory research group (INSERM UMR 957) of 65 people at the Faculty of Medicine, where the pathogenesis of primary bone tumours, and more specifically, the role of bone microenvironment (osteoclasts, mesenchymal stem cells, OPG/RANK/RANKL, IL-6 and MCSF cytokine family) in tumour growth is studied. He is also Associate Editor of Life Sciences, Academic Editor of PLoS ONE, Editor-in-Chief of the Open Bone Journal and serves on the Editorial Board of Current Medicine Chemistry, European Journal of Pharmacology, and Journal of Bone Oncology.

Apoptosis and Drug Resistance in Malignant Bone Tumors

Chapter 36 focuses on apoptosis – physiological cell death that occurs in eukaryotic organisms – and drug resistance in malignant bone tumors. Please read through it, and let us know what you think in the comments below!

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